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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG8
All Species:
22.73
Human Site:
S146
Identified Species:
55.56
UniProt:
Q8ND04
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8ND04
NP_060619.4
991
109684
S146
Q
A
Y
Y
S
Q
E
S
K
V
L
Y
L
L
L
Chimpanzee
Pan troglodytes
XP_523682
991
109658
S146
Q
A
Y
Y
N
Q
E
S
K
V
L
Y
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001107695
991
109808
S146
Q
A
Y
Y
N
Q
E
S
K
V
L
Y
L
L
L
Dog
Lupus familis
XP_548236
991
109617
S146
Q
A
Y
Y
N
Q
E
S
K
V
L
Y
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE18
991
109648
S146
Q
A
Y
Y
N
Q
E
S
K
V
L
Y
L
I
L
Rat
Rattus norvegicus
XP_213430
991
109700
S146
Q
A
Y
Y
N
Q
E
S
K
V
L
Y
L
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415875
961
106103
G139
E
S
R
E
N
G
P
G
V
P
L
P
H
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695811
916
101466
H124
W
K
A
A
E
K
E
H
C
L
Q
L
L
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122102
845
95086
H96
I
I
L
T
H
P
T
H
T
F
D
Y
S
Y
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795158
460
51519
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.9
97.5
N.A.
96
95.3
N.A.
N.A.
83.1
N.A.
65.7
N.A.
N.A.
33.7
N.A.
20.4
Protein Similarity:
100
99.9
99.3
98.3
N.A.
97.7
97.3
N.A.
N.A.
89
N.A.
76.9
N.A.
N.A.
49.8
N.A.
30.2
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
N.A.
33.3
N.A.
N.A.
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
10
10
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
0
10
10
0
70
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
20
0
0
0
0
10
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
0
0
20
0
% I
% Lys:
0
10
0
0
0
10
0
0
60
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
10
70
10
70
40
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
10
0
10
0
0
0
% P
% Gln:
60
0
0
0
0
60
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
10
0
0
60
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
60
0
0
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
60
60
0
0
0
0
0
0
0
70
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _